Age Proof: The New Science of Living a Longer and Healthier Life The No 1 Intern

The Nile on eBay   Age Proof by Professor Rose Anne Kenny, Rose Anne Kenny

One of the world's leading scientists on ageing delivers a revealing and enjoyable account of what ageing is and how we can tackle its more serious side effects.

FORMATPaperback LANGUAGEEnglish CONDITIONBrand New Publisher Description

***SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2022***Did you know that we can lead longer and healthier lives by making simple changes right now?Professor Rose Anne Kenny has 35 years of experience at the forefront of ageing medicine. In Age Proof, she draws on her own pioneering research and the latest evidence to demystify why we age and shows us that 80% of our ageing biology is within our control: we can not only live longer lives but become happier and healthier deep into our later years.Effortlessly distilling scientific theory into practical advice that we can apply to our everyday lives, Professor Kenny examines the impact that food, genetics, friendships, purpose, sex, exercise and laughter have on how our cells age. This illuminating book will show you the steps you can take to stay younger for longer - and will prove that you really are just as young as you feel.

Author Biography

Professor Rose Anne Kenny is an award-winning physician and researcher who has been Head of the academic department of Medical Gerontology at Trinity College Dublin since 2006. She is the founding Principal Investigator of The Irish LongituDinal study on Ageing (TILDA).Prof Kenny has published over 600 scientific publications to date and was admitted as a Member of the Royal Irish Academy (M.R.I.A) in 2014 - Irelands highest recognition for scientific excellence.She recently received a Lifetime Achievement Award for her research on ageing at the world congress in Kuala Lumpur 2019. She was voted a Health Hero by The Irish Times in 2018; won the Trinity Innovation Award in 2017 and was elected President of the Irish Geriatrics Society in 2020.

Review

'A timely call to safeguard our health and vitality' - Irish Times'An essential roadmap to ageing well that's full of good sense and optimism' - Irish Examiner'Professor Rose Anne Kenny reveals in her new book what you should do now to change the rest of your life' - The Times''A very readable and stimulating survey of ageing, strong both on the science of ageing, and on our experiences of getting older. It is wide ranging, blending succinct descriptions of the biological, social and psychological underpinnings of the ageing process with practical advice about how to age in a healthier way, covering issues such as exercise, mindfulness, diet, and the maintenance of social relationships and engagement with life. I can highly recommend this book'' - Professor Andrew Steptoe, Professor of Psychology and Epidemiology, UCL and Director of English Longitudinal Study of Ageing''Dr. Rose Anne Kenny combines decades of loving, hands-on, bedside expertise with state of the art science and a delightful Irish voice to give not only hope but even joyful anticipation to the privilege of growing older. Age Proof is evidence that aging is for everyone'' - Stacy Tessler Lindau, MD, MAPP, Catherine Lindsay Dobson Professor, Departments of Obstetrics and Gynecology and Medicine-Geriatrics, University of Chicago

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One of the world's leading scientists on ageing delivers a revealing and enjoyable account of what ageing is and how we can tackle its more serious side effects.

Excerpt from Book

Your attitude keeps you young (or not) It turns out that the inspirational Instagram quote "Age is not a number" is based on science. Our work and other research confirms that we are indeed as young as we feel. One of our studies showed that people who feel their chronological age are more likely to develop physical frailty and poor brain health than those who claim to feel younger than they are. Older adults with negative perceptions about ageing are likely to die seven and a half years earlier, mostly because of higher rates of heart disease. Meanwhile, feeling younger than our years - irrespective of whatever diseases or disorders we might have - slows the pace of ageing. How? Because a positive attitude towards getting older changes cell chemicals beneficially, possibly by reducing inflammation (low-grade chronic inflammation, from impaired immune responses, is associated with accelerated ageing and many age-related conditions). Even if we have health problems, attitude dominates. A unique piece of research - the Nun Study - perfectly illustrates this. The 678 sisters of School Sisters of Notre Dame in the US took part in a longitudinal study, undergoing regular health and psychological tests, plus a post-mortem brain pathology study. (A great advantage was that they lived similar lifestyles.) Broadly, it was found that the nuns who expressed more positive emotions lived on average a decade longer than their less optimistic peers, and were less likely to get dementia. Aged 80, sixty percent of the least happy nuns had died. But society''s attitudes matter too. Ageism - being forced to retire rather than choosing for oneself for instance - is pernicious and detrimental. A Yale University study showed how perceptions about ageing can change our physiology. Exposure to positive ideas about ageing - eg. words like ''sage'' - helped participants deal with stress. A barrage of negative stereotypes - eg ''senile'' - increased stress, prompting higher blood pressure and heart rate. Don''t stand for ageism - it has directly damaging effects on health. Find your purpose Having purpose is a psychological strength, key to a contented, longer life. Yet sometimes as we age, we lose sight of this. Families dissipate, we retire, our social life shrinks. So how do we find meaning, even in the most challenging of situations? Proven effective is nurturing our creativity. I am director of the newly established Mercer''s Institute for Successful Ageing, at St James''s hospital in Dublin. This clinical and research facility includes a central hub for patients and staff to be creative - through poetry, song, painting and music. Neurological research shows that making art improves not just mood but cognitive function by forming thicker and stronger new connections between brain cells. At the very least, you might visit a gallery - even viewing art has a positive effect. We can also rediscover purpose by taking on new challenges. Abundant data shows that people who volunteer are less depressed and enjoy better quality of life. For some, religion provides meaning. Overall, religious involvement, belief and spirituality are linked to lower depression and anxiety, better memory, better planning and organising abilities, and longer life - though the social factor may be significant in this too. Longevity Good friends add years to our lives. Examining the association between social bonds and health, I was staggered by the powerful physical effects of friendship. But why would the strength of our social contacts and social engagement affect mortality? It''s been suggested that they lower levels of stress and stress-related hormones, heart disease and inflammation. Supporting this explanation, Harvard researchers recently found that greater friendship and familial bonds independently predict lower concentrations of fibrinogen, a clotting factor in blood, a cause of blood clots and heart attacks, and an indicator of inflammation. The association between fibrinogen and social isolation, conversely, was remarkable - it was as bad as smoking. (Important note: if relationships are strained - whether family, partner, or friend - chronic disease was more likely.) Brain health Another Harvard study found that people who enjoyed strong social bonds into their eighties were less likely to succumb to cognitive decline and dementia. The fact that social, mental and physical stimulation through friendships reduce vascular diseases is relevant here too. High blood pressure, high cholesterol, heart irregularities such as atrial fibrillation in midlife, are all associated with Alzheimer''s in later life. The stress-busting effects of good friendships is another reason these relationships benefit brain health. A higher susceptibility to stress doubles the risk of dementia by triggering chronically high cortisol levels. A third theory as to why friendships are brain-protective is that mental stimulation provided by social contacts increases the formation of new brain cells, building up capacity or "cognitive reserve" in the area that converts short term memory to long-term memory, the area important for concentration, understanding, awareness, thought, language, and consciousness, and the area governing our sense of smell. So even if people have abnormal proteins in their brain cells (dementia pathology) they don''t show signs of the disease - their reserve capacity enables normal function. Laughter We laugh more when we''re with friends - laughter bonds us with others. As well as boosting endorphin levels, laughter is a form of muscular exercise, good for circulation and digestion. Fundamentally, it''s a different way of breathing. We''re using the muscles between our ribs to repeatedly blow air out from the lungs without inhaling. It increases the pressure in the chest by effectively breath-holding and stopping the normal rhythmic flow of air in and out. A good belly laugh provides a workout for the diaphragm, abs, and shoulders - plus the immune system and heart. It''s beneficial at a chemical level because it lowers the stress hormones cortisol and adrenaline. And low cortisol stabilises blood sugars and insulin, regulates blood pressure, and reduces inflammation. (NB. Even if we anticipate having a laugh, our positive hormonal system kicks in - rising as much as 87 percent. The same expectation muted stress hormones by up to 70 percent. Time to revisit Seinfeld or Father Ted?). >Why stress is ageing - how we react is key - 7 protective tactics We all know how stress feels to us - but its medical definition is "the quality of experience, produced through a person-environment transaction that, through either over arousal or under arousal, results in psychological or physiological distress." Stress has many biological measures - it affects our nervous system, hormones, immune system and metabolic systems. Persistent stress can lead to obesity, diabetes, high blood pressure, a fast heart rate, heart attacks and strokes. A visible measure of how acute stress can age us is that it can turn hair grey. Harvard researchers found that stress activates the sympathetic nerves - part of the flight or fight response. Examining the impact of stress on the hair follicle, they found that these nerves, which feed the follicles, release the chemical noradrenaline. The intensity of its release depletes hair pigment - as well as accelerating hair loss. Greying, they concluded, is indicative of the biological effects of stress. (The silver lining - their research lays the groundwork for discovering how stress impacts other tissues and organs - a step towards eventual treatment to halt its adverse impact.) Meantime, these techniques can provide a buffer against stress: Acclimatise to regular periods of switching off - for instance, a time each day when phone and internet are out of bounds. Develop routines to de-stress so that it doesn''t become chronic. Confess your worries to a friend. University of Southern California researchers tested the saying "a problem shared is a problem halved" - they found it does indeed reduce stress, lowering cortisol. Take up gardening. A recent paper analysed 22 studies on gardening and health - its host of positive effects include reductions in depression, anxiety, and BMI, plus a rise in life satisfaction, and quality of life. No garden or window box? Go for a walk. In nature, preferably - forests have a notably calming effect. But our body loves motion and walking per se is beneficial. Our mood improves, stress levels fall, creativity increases dramatically. Even walking indoors on a treadmill facing a blank wall (as opposed to sitting down) enhances creativity. Eat meals with others when possible. If sitting down with family or friends just once a week is achievable, make it an honoured routine. Keep the food simple so it doesn''t become a chore, share responsibility, and plan it. Proven techniques to lower stress include controlled breathing, meditation, and dispositional mindfulness - take your pick. Brain scans show that meditation preserves the brain''s main structural tissues. It also potentially suppresses processes that contribute to brain ageing. Dispositional mindfulness meanwhile - a keen attention to present thoughts and feelings - has physical, psychological, and cognitive benefits (it''s the opposite of letting our mind wander, fretting about the future.) You''ve heard this before but - consider yoga. As well as improving balance and flexibility, at a cellular level, it reduces inflammation and thereby slows biological ageing. Several studies show that yoga increases the length of telomeres - the protective coverings at the end of chromosomes which stop chromosomal damage. (With ageing, t

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One study showed a difference of 20 years in biological ageing clocks in adults as young as 38. The good news is that it's within our power to modify and improve most of the factors that influence our clocks. We control 80 percent of our ageing biology, says Professor Kenny. (Banning ageist language and attitudes is a good start.) Kenny, whose sub speciality is cardiovascular medicine, is also founder and Principal Investigator of the Irish Longitudinal Study on Ageing (TILDA) - which has followed almost 9,000 adults aged fifty and older, and generated over 400 research papers. The study covers all aspects of life - from sex to food, to physical and brain health, genetics, childhood experience, expectations, friendships, finance and much more - to illustrate why and how we age. Most of us are eager to know more about ageing and health. Yet at the same time many people in midlife tell her they can hardly bear to think about growing old, such is their dread of it. But, she writes, the "last lap" - as one of her patients cheerily calls it - can be the most relaxed, worthwhile and contented period of our lives, especially if we prepare for it. So if you'd like to enjoy a longer, happier, healthier existence, here is the expert's advice, after 35 years at the forefront of ageing medicine.

Details ISBN1788705068 Author Rose Anne Kenny Short Title Age Proof Language English Year 2023 ISBN-10 1788705068 ISBN-13 9781788705066 Format Paperback DEWEY 612.68 Pages 336 Publisher Bonnier Books Ltd Publication Date 2023-01-05 UK Release Date 2023-01-05 Place of Publication Chichester Country of Publication United Kingdom AU Release Date 2023-01-05 Imprint Lagom Subtitle The New Science of Living a Longer and Healthier Life The No 1 International Bestseller Audience General NZ Release Date 2023-07-03 We've got this

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